Arsenal have been handed a tough test as the team will face reigning Champions League winner, Barcelona in the round of 16 stage scheduled to begin in February.
Also, Chelsea will challenge its perennial rival, Paris Saints Germain while high-flying Bayern Munich will confront Juventus in a mouth-watering encounter.
In the other fixtures, Manchester City will tackle Dynamo Kieve as Real Madrid face Roma.
Gent host Wolfsburg while PSV welcome Atletico Madrid.
Finally, Benfica will host Zenith.
English Premier League
Arsenal will face the Blues at Emirates stadium tomorrow.